As an essential nutrient for the human body, Vitamin B12 is responsible for producing a variety of substances and maintaining the normal operation of multiple functions of the body, but the body can not synthesize by itself, and must be supplemented by external intake, knowing that it is simple to supplement. However, the question is when do we need to supplement Vitamin B12?After a lack of vitamins, the body may experienceFatigue and fatigue, dizziness, pale complexion, depression, glossitis, jaundiceThere are various symptoms, but these are allNon-specificMany diseases can cause similar symptoms

As an essential nutrient for the human body, Vitamin B12 is responsible for producing a variety of substances and maintaining the normal operation of multiple functions of the body, but the body can not synthesize by itself, and must be supplemented by external intake, knowing that it is simple to supplement. However, the question is when do we need to supplement Vitamin B12?

After a lack of vitamins, the body may experienceFatigue and fatigue, dizziness, pale complexion, depression, glossitis, jaundiceThere are various symptoms, but these are allNon-specificMany diseases can cause similar symptoms. Therefore, it is difficult to identify Vitamin B12 deficiency clinically. This is not true, although it is a young person who values health, Xiao Yang did not notice either.

Xiao Yang advocates vegetarianism and has always believed that it is the healthiest dietary plan. But recently, it seems that Xiao Yang's body has been experiencing problems. Initially, he only appeared after waking up from sleepBurn and tingling sensation in the thighsUnexpectedly, one day laterSwelling appeared at the kneeSo immediately went to the hospital for medical treatment.

The first doctor drew blood and checked uric acid, but no abnormality was found. The second doctor suggested taking the accumulated fluid at the knee for test. The third doctor suspected that it was Shingles virus infection. After several diagnoses and treatments, Xiao Yang's symptoms were not alleviated.

At a loss, a doctor, after carefully understanding Xiao Yang's symptoms and dietary habits, came up with the possibility thatInadequate intake of Vitamin B12So it was decided to undergo another blood test for vitamin deficiencySure enough, the examination results showed that Xiao Yang was deficient in Vitamin B12, so he was prescribed painkillers and mecobalamin tablets. After eating a bottle, Xiao Yang recovered completely.

From Xiao Yang's case, it can be seen that the treatment of Vitamin B12 deficiency is actually very simple. It can be supplemented in time. The difficulty lies in the diagnosis. After many setbacks, many people draw blood and take CT scans. Finally, they found that a box of a few yuan of mecobalamin could be easily solved, so they had to pat their legs and shake their heads and sighs.

At this point, you may have questions,Vegetables and fruits should be rich in vitamins. Why are Vegetarianism easy to lack Vitamin B12?What do we often mean by B vitamins? Don't worry, just listen to me slowly.

Small cobalamin, containing a vast universe

The only nutrient containing metallic elements and essential mineralsWidely present inMeat, seafoodIn,soybeanIt also contains Vitamin B12.

Some people areInsufficient intakeIt leads to the lack of Vitamin B12, and some peopleAlthough Vitamin B12 intake is sufficient,It may also be due toGastrointestinal dysfunctionCausing inability to absorb and ultimately resulting in deficiency. The metabolism and absorption process of Vitamin B12 in the human body is very complex, and the specific process is as follows.

Human body through consumptionAnimal liver and kidney, eggs, dairy products, and other foodsSupplement Vitamin B12. These foods are digested and decomposed by Pepsin and trypsin in the gastrointestinal tract, which dissociates the VB12 contained from the food. At the same time, Parietal cell produce intrinsic factor (IF), which forms VB12-IF complex with VB12.

It arrivedTerminal ileumWhen it is recognized by the receptor, IF is dissociated from the complex. Vitamin B12 enters the cell through Pinocytosis and binds to the cobalt transferrin II synthesized by the liver, which is distributed in the blood and various tissues and cells.

Vitamin B12 is largely stored after being absorbed by the human body. Why is it still lacking?

Actually, in terms of diet, there are onlyCompletely vegetarian or severely picky eatersInsufficient intakeappear,B12After total Gastrectomy or subtotal gastrectomyLacking of parietal cells and endogenous factors, the absorption process of Vitamin B12 is abnormal.

haveSmall intestine bacterial hyperproliferation syndrome, history of ileectomy surgery, ileal bypass surgery, long-term hemodialysisB12,have,.

,B12,appear,.B12,have

B12havehave

B121-10mg,And through.In,MM-CoA,DNA,.

,DNAIn,B12Met,Participate in the transfer process of methyl groups and the Met cycle process.

,N5-CH3-FH4B12,N5-CH3-FH4FH4.,B12DNA,,.

Vitamin B12 can also promote homocysteine (hcy) deadenosine conversion into Met in the Met circulation process, reducing Hcy in the blood,Reduce the risk of Atherosclerosis and coronary heart disease.

Because the imbalance of methylation and high Hcy is one of the causes of central nervous system abnormalities, Vitamin B12 is involved in the transformation of methylation and HcySynthesis of neural myelin sheath.

2022B12AD,90AD,,B12,B12,.

The results showed that the curative effect of the group using folic acid and Vitamin B12 was higher than that of the control group, which further demonstrated that Vitamin B12 couldImprove and maintain nervous system function, improve cognitive function and memory.

,B12AA,CoA,ALAALA,.

Therefore, Vitamin B12 can alsoPromote the synthesis of hemoglobin and assist in the synthesis and maturation of red blood cells,.

In summary, vitamin B12 is present inSynthesis of nucleic acids and proteins, maintenance of nervous system function, and generation of red blood cells,,appear,appear,,B12.

In these cases, it will be too late to supplement Vitamin B12!

B12,B12,appearB12.

1. Megaloblastic anemia

havePale complexion, dizziness and fatigueNon-specific,appear,B12.

B12,B12,.,.

2. Tongue inflammation and pain

Patients lacking Vitamin B12 may also haveTongue nipple atrophy and tongue mucosal ulcerWait, why is this?

After the normal person accidentally bites the tongue, the machine will quickly help it heal, but the healing speed of the Vitamin B12 deficient person is significantly slower than that of the normal person, which may be related to the normal growth andThe update is disrupted and the ability to split is reducedhave.

,haveB12have,have.

3. Slow thinking and low emotions

,appear,,however,B12appear.

B12,.B12The oxygen supply to brain cells may be insufficient,The metabolism of the central nervous system and the integrity of nerve fibers may also be affected,Secondary demyelination ,,.

100100,B12Hcy.

,B12,Hcy,have.Tiemeier,People lacking Vitamin B12 are more likely to suffer from depression.

4. Thrombosis or Atherosclerosis

B12Met,Increased Hcy level,HcyBinding to vascular endothelial cells,,,.

,HcyBinding to platelets,.,have.

,appearPale complexion, dizziness and fatigue,.

B12,,,.

Wisdom on supplementing Vitamin B12

B12,,Removing triggers and treating diseases,B12.Oral medication,Injectable preparations,.

,B12,haveB12,have,.

howeverMiddle aged and elderly people with impaired digestive function,.,Actively seek medical attention,Injectable preparations.

Especially for gout patientsIt is not recommended to blindly supplementB12,B12,,.

however,,B12,have,.Pflipsen MCHermann LSde Jager JKos ELong term use of Metformin may cause the decrease of Vitamin B12 level,Terminal ileum-have.

B12,B12,.

Write at the end

B12B,,,,,.

appearB12,,And throughOral or Intramuscular injectionSupplementary methods; Do you understand?

Reference:

[1] Li Jin, Xu Huashan. Serum Vitamin B_ (12) Correlation analysis between levels and depressive status [J]. Chinese Journal of Food and Nutrition, 2022-28 (08): 67-69+76

[2] Expert consensus on clinical application of Metformin (2016 edition) [J]. Chinese Journal of diabetes, 2016,24 (10): 871-884

Disclaimer: The content of this article is sourced from the internet. The copyright of the text, images, and other materials belongs to the original author. The platform reprints the materials for the purpose of conveying more information. The content of the article is for reference and learning only, and should not be used for commercial purposes. If it infringes on your legitimate rights and interests, please contact us promptly and we will handle it as soon as possible! We respect copyright and are committed to protecting it. Thank you for sharing.(Email:[email protected])